Coverage dated September 22, 2026

The gene-regulatory evolution of the human skeleton

Headline from Nature

Nature, Published online: 23 September 2026; doi:10.1038/s41586-026-11053-x Massively parallel reporter assays and human–ape hybrid skeletal cells are used to study the evolution of human cis-regulatory elements (CREs), revealing how differences in CREs have shaped the composition of human skeletal …

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Reports & sources

2 articles, oldest first.

  1. Nature

    The gene-regulatory evolution of the human skeleton (opens Nature)

    Published

    Nature's feed description

    Nature, Published online: 23 September 2026; doi:10.1038/s41586-026-11053-x Massively parallel reporter assays and human–ape hybrid skeletal cells are used to study the evolution of human cis-regulatory elements (CREs), revealing how differences in CREs have shaped the composition of human skeletal …

  2. Nature

    The human skeleton’s unique adaptations relied on gene regulatory changes (opens Nature)

    Published

    Nature's feed description

    Nature, Published online: 23 September 2026; doi:10.1038/d41586-026-02775-z Variants in genes involved in the production of extracellular matrix molecules could have enabled the skeletal adaptations that distinguish humans from other great apes.

The gene-regulatory evolution of the human skeleton | Since Then