Three-Photon Microscopy Reveals Neural Activity Deep in the Mouse Brain
Headline from Geneng News
By optimizing laser, optical, and acquisition parameters, The Rockefeller University researchers developed a three-photon microscopy platform that captures deep-brain neural activity in living mice at single-cell resolution without surgically removing the overlying cortex.
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As light travels deeper into the brain, it scatters. Three-photon microscopy, the current state of the art, reduces the resulting background fluorescence and can, in principle, image much deeper than earlier techniques—but to do that, it uses average laser power limits that cause overheating and dam…
By optimizing laser, optical, and acquisition parameters, The Rockefeller University researchers developed a three-photon microscopy platform that captures deep-brain neural activity in living mice at single-cell resolution without surgically removing the overlying cortex.
Three-Photon Microscopy Reveals Neural Activity Deep in the Mouse Brain | Since Then
